In People With Sickle-Cell Disease, Red Blood Cells Break Down, Clump, And Clog Blood Vessels. Blood Vessels And Broken Cells Accumulate In The Spleen. Among Other Symptoms, This Leads To Physical Weakness, Heart Failure, Pain, And Brain Damage. Such A Suite Of Symptoms Can Be Explained By __________.. As people with sickle cell disease grow older, they may develop chronic pain, for reasons that remain unclear. Sickle cell disease (scd) is a hereditary blood disorder characterized by the production of abnormal hemoglobin molecules that cause red blood cells to take on a crescent or sickle.

Sickle cell disease is an inherited blood disorder in which the body produces abnormally shaped red blood cells. As people with sickle cell disease grow older, they may develop chronic pain, for reasons that remain unclear. In people with with sickle cell, red blood cells form into a crescent, sickle shape that break apart easily, clump together, and block the flow of blood.